کتاب دانلود کتب لاتین علوم پزشکیداروشناسی و آنتی بیوتیک
تبلور کروی به عنوان یک بستر جدید برای مهندسی طراحی ذرات
تبلور کروی به عنوان یک بستر جدید برای مهندسی طراحی ذرات

Spherical Crystallization as a New Platform for Particle Design Engineering
نویسنده: Yoshiaki Kawashima
سال انتشار: 2019
تعداد صفحات: 130
زبان فایل: English
فرمت فایل: pdf
حجم فایل: 7MB
قیمت: 200,000ريال

افزودن به سبد دانلود

Publisher : Springer

ISBN-10 : 9811367876, 981136785X

ISBN-13 : 978-9811367878, 978-9811367854

ASIN : B07S5KVMHL

This book describes the principles and applications of the spherical crystallization technique, from the standpoint of its inventor. After an introduction on the history of particle design engineering and nanotechnology, the concept of spherical crystallization itself is clearly explained. Attention then turns to the application of spherical crystallization in pharmaceutical processes. It is explained how the technique can provide physicochemical properties suitable for direct tableting of active pharmaceutical ingredients and how it has enabled the development of a novel particulate design platform from single to complex system. Subsequent chapters describe the roles of polymeric spherical crystallization in the preparation of novel microspheres, microballoons for drug delivery systems (DDS) and the development of biocompatible and biodegradable poly(D,L-lactide-co-glycolide) (PLGA) nanospheres. The various applications of PLGA nanospheres composite within oral-, pulmonary-, transdermal DDS and cosmetics are fully discussed. Finally, future perspectives are presented on use of the technology in the design and industrial-scale manufacture of new drug delivery systems, highlighting how a continuous pharmaceutical process that meets US Food and Drug Administration quality requirements should soon be introduced.