This review aims to summarize evidence on the effectiveness of interventions to improve antihypertensive drug adherence in Latin America and the Caribbean.
A systematic search from January 2000 to October 2018 was conducted through LILACS, SciELO, MEDLINE, Health Evidence, Cochrane Library and Embase. Search terms were in English, Portuguese and Spanish through the MeSH and DECS.
Seven articles were included in the study. The main discoveries indicate that implemented interventions to increase the adherence are very varied. Likewise, a high variability in levels of adherence was found (46–94%) and we could evidence that indirect measurements were used. Lastly, it was evidenced that the obstacles for adherence were mainly associated with the adverse effects of antihypertensive medication, the dosage and forgetfulness of the medication intake given the age of the patients.
There is no single strategy to increase pharmacological adherence in Latin America since the studies used different strategies. Additional efforts are required to standardize cost-effective interventions to increase pharmacological adherence in Latin America.