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بررسی عوامل ژنتیکی میزبان مرتبط با مالاریا
بررسی عوامل ژنتیکی میزبان مرتبط با مالاریا

Exploration of Host Genetic Factors associated with Malaria
نویسنده: Tabish Qidwai
سال انتشار: 2021
تعداد صفحات: 174
زبان فایل: انگلیسی
فرمت فایل: pdf
حجم فایل: 5MB
قیمت: 100,000ريال

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Publisher : Springer

ISBN-10 : 9813347600

ISBN-13 : 978-9813347601

ASIN : B08YDWV3QW

This book is aimed to cover the role of genetic polymorphisms in human genes related to RBC disorders, metabolic enzymes, immune response, and cytoadherence in the susceptibility/resistance to malaria caused by Plasmodium falciparum. The chapters provide current information on the balancing trait and the significance of such traits in the malaria resistance. The book covers polymorphisms in the genes of the red blood cells-sickle cell anaemia; glucose-6-phosphate dehydrogenase deficiency and thalassemia that confer protection against malaria. In addition, the book explores selection of genetic variations in the human genome as genetic control mechanism against malaria in endemic regions. It also provides a comprehensive overview of the molecular epidemiology and natural selection of alleles in the genes which are associated with malaria, and presents description of the role of human genetic polymorphisms in malaria disease risk and disease outcome.