CRISPR: Biology and Applications

“An  excellent compendium of all things CRISPR from some of the leading  minds in the field. With thorough coverage from every angle and  beautifully detailed illustrations, this book is not to be missed!” 

Jennifer A. Doudna,
Professor  of Chemistry, Biochemistry & Molecular Biology, UC Berkeley;  Founder, Innovative Genomics Institute; Nobel Laureate and coinventor of  CRISPR technology

“This  journey through CRISPR biology and several of its breakthrough  applications offers an exciting glimpse into one of the most beautiful  and compelling fields in the life sciences.” 

David R. Liu,
Director  of the Merkin Institute at the Broad Institute of MIT and Harvard;  Professor of Chemistry and Chemical Biology at Harvard University;  coinventor of base editing and prime editing

“A  must read! The CRISPR topics, written by world-leading experts, span  from the fascinating mechanistic underpinnings to the ingenious  applications. One can read from start to finish or pick and choose  themes. Either way, the book delivers utterly enjoyable learning!” 

Bonnie Bassler,
Squibb Professor and Chair, Princeton University Department of Molecular Biology; Howard Hughes Medical Institute Investigator

CRISPR-Cas  systems have revolutionized the science of gene editing and their  possible applications continue to expand, from basic research to  potentially groundbreaking medical and commercial uses.

Led by a distinguished team of editors, CRISPR: Biology and Applications explores the subject matter needed to delve into this fascinating area. Topics covered include:

• Classification and molecular mechanisms of CRISPR-Cas systems
• CRISPR-Cas evolution, regulation, expression, and function
• Uses for gene editing and modulation of gene expression
• CRISPR-based antimicrobials and phage resistance for medical and industrial purposes

Written by internationally renowned authors, CRISPR: Biology and Applications serves as both an introductory guide for those new to the field and an  authoritative reference for seasoned researchers whose work touches this  evolving and headline- making science.