In the name of Allah the Merciful

Diagnostics and Gene Therapy for Human Genetic Disorders

K.V. Chaitanya, 2022035247, 2022035248, 9781032381640, 9781032381657, 9781003343790, 978-1032381640, 978-1032381657, 978-1003343790

10 $

English | 2022 | PDF

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Diagnostics and Gene Therapy for Human Genetic Disorders provides an  integrative and comprehensive source of information blending classical  human genetics with the human genome. It provides a multidisciplinary  overview of Mendelian inheritance and multifactorial inheritance,  genetic variations, polymorphisms, chromosomal, multifactorial, and  mitochondrial disorders.

PCR, electrophoresis, cytogenetics,  prenatal, and HPLC based techniques applied for diagnosing genetic  disorders are discussed with applications. Symptoms, etiology,  diagnosis, treatment of 14 major and 5 minor genetic disorders are  discussed in detail. Methods employed for the preparation of kits for  the diagnosis of diseases are provided. The role of gene therapy in the  amelioration of genetic disorders and the methodology employed are  discussed. The success of gene therapy in controlling various disorders  such as immune system disorders, neurodegenerative disorders,  cardiovascular disorders, eye diseases, and cancer has been described  along with type studies.

Features
1. A blend of classical human genetics with molecular and genome-based applications
2. Techniques applied for the diagnosis of genetic disorders
3. Diagnostics of 19 genetic disorders including symptoms, etiology, diagnosis, and treatment.
4. Role of gene therapy in the amelioration of disorders
5. Type studies describing the role of diagnostics in conserving the human health.

This  book attempts to connect all the information about classical and modern  human genetics, genetic disorders, and gene therapy to all types of  diseases in one place. This work provides a comprehensive source of  information that can serve as a reference book for scientific  investigations and as a textbook for the graduate students.