Hydrogen Sulfide: Chemical Biology Basics, Detection Methods, Therapeutic Applications, and Case Studies

Covers H2S interactions, methods of detection and delivery in biological environments, and a wide range of applications

Research  on hydrogen sulfide (H2S) spans diverse disciplines including  chemistry, biology, and physiology. In recent years, new materials and  approaches have been developed to deliver H2S and related reactive  sulfur species in various clinical contexts. Although many biological  pathways involving H2S are complex, all are governed by fundamental  chemical interactions between reactive sulfur species and other  molecular entities.

Hydrogen Sulfide: Chemical Biology Basics,  Detection Methods, Therapeutic Applications, and Case Studies provides  the foundation required for understanding the fundamental chemical  biology of H2S while highlighting the compound’s therapeutic potential  and medicinal applications. This book covers key aspects of H2S chemical  biology, including the fundamental chemistry of reactive sulfur  species; the measurement, detection, and delivery of H2S in biological  environments; and the therapeutic and medicinal uses of exogenous H2S  delivery in various pharmacologically relevant systems. Throughout the  text, editor Michael Pluth and chapter contributors discuss the  opportunities and future of the multidisciplinary field.
Provides  approaches for delivering H2S with relevance to biological and  therapeutic applicationsDescribes complex interactions of H2S with  bioinorganic complexes and reactive sulfur, nitrogen, and oxygen species  Summarizes advances in available tools to detect, measure, and modulate  H2S levels in biological environments, such as real-time methods for  H2S fluorescence imaging in live cell and animal systems Helps readers  understand known systems and make connections to new and undiscovered  pathways and mechanisms of action Includes in-depth case studies of  different systems in which H2S plays an important role
Hydrogen  Sulfide: Chemical Biology Basics, Detection Methods, Therapeutic  Applications, and Case Studies is an important source of current  knowledge for researchers, academics, graduate students, and industrial  scientists in the fields of redox biology, hydrogen sulfide research,  and medicinal chemistry of small biological molecules.