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Understanding PTMs in Neurodegenerative Diseases

Victor Corasolla Carregari, 3031054598, 9783031054594, 978-3031054594

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English | 2022 | PDF

This new volume, a part of the Proteomics, Metabolomics, Interactomics  and Systems Biology series, will explain how proteomic studies of  post-translational modifications (PTMs) can be applied to  neurodegenerative diseases and relevant studies. The goal of the book is  to increase awareness among researchers about how PTMs may be helpful  in understanding mechanisms in various neurodegenerative diseases  through proteomic studies. This book will serve as a tool for those who  want to begin work in the proteomics field and explore how to implement  PTMs studies into their work. Chapter authors will describe different  PTMs enrichment methods developed by experts in the field so that  researchers may learn to apply these methods and techniques to new  studies. Divided into three sections, chapters will cover sample  preparation, data quality, enrichment techniques, guidelines on how to  analyze PTMs, and explain the role of PTMs and different brain diseases.  Among those topics includes will be brain cancer, SLA disease,  Parkinsons disease, muscular dystrophies, and schizophrenia. This volume  will be useful for researchers and students studying brain and  neurodegenerative diseases who are interested in delving into work with  proteomic studies and PTMs. 

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