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Vertebrate Motoneurons

Michael J. O'Donovan, Mélanie Falgairolle, 3031071662, 9783031071669, 978-3031071669

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English | 2022 | PDF

This book aims to provide a comprehensive and timely review of new  findings in motoneuron research. Recent findings have revealed that  motoneurons are more complex and have more extensive functions than  previously imagined. Some of the molecular and genetic pathways that  orchestrate the development of motoneurons have been discovered, as have  the mechanisms responsible for the selective innervation of muscles by  specific pools of motoneurons. These novel findings are revolutionizing  ideas about the function of motoneurons and have important implications  for motoneuron disease.  

Chapters from several of the foremost  figures in the field are included in this book and will emphasize how  basic science is the engine driving the discovery of novel treatments  for degenerative motoneuron diseases. Cutting edge developments in the  use of pluripotent stem cells to correct motoneuron disease will be also  be covered.  This book would be useful to students of basic motoneuron  physiology, locomotor behavior and motor control. This book would also  be of interest to professional neuroscientists, neurologists, and  neurosurgeons.

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